The Intrepid Just Died, Captain (The Immunity Syndrome)

The Federation Constitution-class starship USS Intrepid was destroyed by a giant space amoeba. On the USS Enterprise NCC-1701, Spock sensed the deaths of the Vulcan crew of the Intrepid. Captain Kirk and Dr. McCoy went to Spock. Kirk asked "Spock, are you all right?" McCoy asked "What is it, Spock? Are you in pain?" Spock turned to Kirk and said "Captain, the Intrepid. She just...died. And the 400 Vulcans aboard, all dead."