Adrian Balboa (neé Adriana Pennino) (March 10, 1950 - January 11, 2002) was the spouse of Rocky Balboa and sister of Paulie Pennino who worked at the pet store near where Rocky lived in the Kensington neighborhood of Philadelphia in the first film Rocky; Rocky and Adrian would later marry in Rocky II where their son, Rocky Balboa, Jr., was born, the only child of the marriage. She is the deuteragonist in Rocky, Rocky II and Rocky IV, tritagonist in Rocky III and Rocky V, and flashback character in Rocky Balboa.
Between the events of Rocky V and Rocky Balboa, Adrian passed away on January 11, 2002, at the age of 51, from ovarian cancer, leaving her husband a widower.